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Author

Jun J. Yang

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Sep 2026

Prevalence of pharmacogenomically implicated prescriptions in multi-ethnic populations in Singapore.

Pharmacogenomically implicated medication prescriptions are common in Singapore and are particularly prevalent in elderly populations, with males prescribed these medications earlier in life than females and Indians and Malays were more likely to be prescribed these medicines at a younger age than Chinese.

Zavier Zhe Xuan Loo, Zhen-Hua Li, Sean Zhuo Xuan Lee et al. · 0 citations
Open access Sep 2026

Bicistronic CD19/CD22 CAR T-Cell Therapy in Pediatric B-Cell Acute Lymphoblastic Leukemia: A Nonrandomized Clinical Trial.

In this nonrandomized clinical trial, bicistronic CD19/CD22 CAR T-cell therapy induced high rates of minimal residual disease-negative remission, with durable EFS in pediatric B-ALL, and support further evaluation in prospective trials.

Xinyu Wan, Yan-Jing Tang, Jiao-Yang Cai et al. · 1 citation
Review Open access Aug 2026

Clinical Functional Assignment of TPMT and NUDT15 Alleles by the Clinical Pharmacogenetics Implementation Consortium Pharmacogene Curation Expert Panel

The work presented here includes the first designation of decreased function alleles for both TPMT and NUDT15, reflecting new clinical data that demonstrate partial loss of enzymatic activity and reduced dose tolerance.

Bailey M. Tibben, Maud Maillard, Victoria M. Pratt et al. · 0 citations

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