An Integrated Strategy for Decoding Bioactive Components and Mechanism of Jingtong Granules: Chemical Characterization, Network Analysis, Pharmacokinetic and Pharmacodynamic Studies.
This study aimed to identify bioactive constituents of Jingtong Granules (JTG), a traditional Chinese medicine for cervical spondylotic radiculopathy (CSR), characterize their in vivo exposure, and explore pharmacological targets and pathways. Chemical constituents were characterized by LC-MS with GNPS-based molecular...