Author

Jun-Jun Yin

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Sep 2026

Phenotypic shift of astrocytes from A1 to A2 induced by fasudil improves demyelination recovery in cuprizone-treated mice

FSD is identified as a promising therapeutic candidate for inhibiting demyelination through the regulation of AST polarization via specific signaling mechanism and ameliorated CPZ-induced demyelination.

Kun Xu, Ting Yang, Hao-Ran Dong et al. · Metabolic brain disease · 0 citations

Open access Aug 2026

SLC7A11-associated astrocyte states are linked to redox imbalance and synaptic microenvironment remodeling in multiple sclerosis: translational implications

SLC7A11-associated astrocyte states are associated with redox imbalance and synaptic microenvironment remodeling in MS and provide a glial-state framework linking neuroinflammation, oxidative stress, and synaptic dysfunction, highlighting potential avenues for translational strategies in MS.

Jian Liu, Jun-Jun Yin, Meng Pu et al. · Journal of Translational Med... · 0 citations