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Author

Jun Li

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Open access Jan 2026

Polydatin Reverses Diabetes‐Induced Apoptosis of Pancreatic β‐Cells by Inhibiting the TNF/TNF‐R1/Caspase‐3 Signaling Axis

Investigating whether PD prevents pancreatic β‐cells against diabetes‐related apoptosis and exploring the associated molecular mechanisms revealed that PD attenuated diabetic β‐apoptosis, likely through inhibition of the TNF/TNF‐R1/caspase‐3 pathway, suggesting that PD may be a novel anti‐DM therapeutic target.

Jun Li, Yi-Fan Zhou, Xue-Tong Wu et al. · 0 citations

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