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Review Aug 2026

Aging at the neurovascular interface: an integrative framework linking cardiovascular and cerebrovascular diseases.

Current evidence on the structural and functional basis of the NVI is synthesized, how aging may disrupt its integrity is discussed, and its potential role as an integrative framework linking aging-related vascular, neural, inflammatory, and extracellular-matrix alterations to cardiovascular-cerebrovascular comorbidity...

Ke-Xin Chen, Jun Ma, Yong Peng · 0 citations
Sep 2026

IL-1β-driven SERPINE1 Upregulation is Associated with CAD-ICM-related Cardiomyocyte Remodeling.

INTRODUCTION Coronary artery disease (CAD) may progress to ischemic cardiomyopathy (ICM) and heart failure through maladaptive cardiomyocyte remodeling and myocardial fibrosis. This study aimed to identify key molecular mediators linking inflammatory and fibrotic signaling during this pathological transition. METHODS...

Ke-Xin Chen, Xing-Yu He, Xiang-Ming Ning et al. · 0 citations

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