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Author

Jun-Nan Jiang

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2 papers indexed here

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Review Open access Sep 2026

The plasticity and metabolic reprogramming of macrophage in ulcerative colitis

Macrophages exhibit phenotypic plasticity, which plays a role in driving tissue injury and promoting mucosal repair in ulcerative colitis (UC). Intestinal macrophages originate from both embryo-derived resident cells and circulating monocytes. Macrophage polarization influences inflammatory responses and is regulated b...

Yi Zhang, Ding-Quan Yang, Jun-Nan Jiang et al. · 0 citations
Review Open access Sep 2026

Phase Separation, Material State, and Condensate Fate in Mammalian Autophagy

Biomolecular phase separation has emerged as a key organizing principle in macroautophagy (hereafter autophagy). In mammalian cells, phase‐separated condensates not only serve as substrates for selective degradation, but also act as dynamic platforms for cargo recognition, signaling integration, and autophagosome assem...

Yuan-Qiang Lin, Mingran Dai, En-Yong Dai et al. · 0 citations

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