Jun Okui

OA02.2. Survival Comparison in Patients With Pathological Complete Response Following Neoadjuvant Chemotherapy vs Chemoradiotherapy in Esophageal Squamous Cell Carcinoma

Esophageal Cancer: Adjuvant and Neo-Adjuvant Therapies In the treatment of esophageal squamous cell carcinoma (ESCC), previous studies have shown comparable overall survival (OS) between neoadjuvant chemotherapy (NAC) and neoadjuvant chemoradiotherapy (NACRT). While NACRT typically yields a higher patholog...

Automated detection of gastroesophageal adenocarcinoma recurrence from electronic health records.

Recommendations for generating real-world evidence with regulatory-grade relevance and reliability

A purpose-oriented framework clarifying the levels of relevance and reliability required according to specific regulatory objectives is proposed, and practical recommendations for generating regulatory-grade RWE that meaningfully informs regulatory decision-making while complementing conventional clinical trials are pr...