Immunomodulatory effects of Sanghuangporus sanghuang polysaccharide SSP1 in cyclophosphamide-induced immunosuppressed mice: associations with gut microbiota, short-chain fatty acids, and metabolic remodeling
Introduction Immunosuppression induced by chemotherapeutic agents such as cyclophosphamide (CTX) is frequently associated with gut microbiota dysbiosis. Sanghuangporus sanghuang polysaccharide (SSP1) possesses immunomodulatory potential; however, its effects on mucosal immunity and the gut microbiota remain unclear. Me...