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Author

Jun-Qi Zhang

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Open access Sep 2026

BAP31 Facilitates TGF-β Trafficking and Secretion and Promotes Dendritic Cell Dysfunction in Cervical Cancer

Cervical cancer remains one of the major gynecological malignancies worldwide, with tumor immune evasion playing a critical role in disease progression. Although accumulating evidence has implicated BAP31 in tumor progression and immune regulation, its role in immune evasion in cervical cancer remains poorly understood...

Lin Guo, Yuan-Li He, Fei-Ming Hu et al. · 0 citations
Review Open access Aug 2026

Molecular innate immune programs of tumor-associated macrophages in immune checkpoint blockade resistance: a staged framework from suppressive circuitry to translational bottlenecks

This review discusses TAM-mediated resistance to ICB as a molecularly regulated innate immune process that is dynamic and adaptive, and proposes that future TAM-directed therapies should move beyond broad macrophage depletion or nonspecific suppression and be matched to dominant macrophage programs, informed by spatial...

Yu-Zhe Huang, Jun-Qi Zhang, Kaipeng Tu et al. · 0 citations

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