Jul 2026
A Helicase-Fused Cas9 improves Large-Size Fragment Knock-in.
MCCas is established as a promising gene editing tool with enhanced ls-KI capacity and relies on the canonical HR pathway, as inhibition of key processes such as end resection and strand invasion abolished the enhancement.
Duowei Zhao, Xiangjie Zhao, Yuhang Gao et al.
· Molecular Therapy · 0 citations