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Author

Jun-Wei Gao

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Review Open access Sep 2026

Immunotherapy of membranous nephropathy: strategic evolution from CD20 monoclonal antibodies to future vaccines

Membranous nephropathy (MN) arises from autoantibody-mediated attack on podocyte antigens, with immune deposits forming subepithelially at the glomerular basement membrane to trigger complement activation and subsequent podocyte damage, eventually manifesting as proteinuria. Traditional therapy hinges on nonspecific im...

Ke-Na Yu, Xi-Fang Xu, Jun-Wei Gao et al. · 0 citations
Review Open access Sep 2026

Cellular senescence of renal tubular epithelial cells in diabetic kidney disease: emerging mechanisms and targeted interventions

Diabetic kidney disease (DKD) is a leading cause of end-stage kidney disease (ESKD), and while current standard treatment strategies can slow disease progression, they are still unable to reverse progressive structural damage to the kidneys. Emerging evidence indicates that the senescence of renal tubular epithelial ce...

Jun-Wei Shi, Jia-Ning Sun, Jun-Wei Gao et al. · 0 citations

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