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Jun-Wen He

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Preprint Aug 2026

UniSpace: Unified Visual Representation and Scalable Multimodal Modeling

Semantic vision encoders have become a central visual interface for multimodal understanding and semantic conditioning in image generation. However, their final tokens discard fine-grained visual details, leading to poor pixel reconstruction and limiting their use in reconstruction-sensitive tasks such as image generation and editing. In this work, we ask whether understanding, generation, and editing can be modeled in a single visual representation space built from a pretrained semantic ViT. We show that the frozen Transformer blocks of a semantic ViT are not intrinsically unable to preserve visual details. Instead, the original patch parameterization drives the representation toward semantic abstraction, making fine-grained information difficult to recover from the final tokens. Based on this observation, we introduce \emph{Patch Reparameterization}, which preserves the original semantic pathway while adding a reconstruction-aware patch embedding that provides fine-grained visual information to the same frozen ViT blocks. The resulting unified representation preserves multimodal understanding while enabling high-fidelity image reconstruction and a favorable reconstruction--generation trade-off. We further scale this representation into \emph{UniSpace}, an 8B Mixture-of-Transformer-Experts model that performs understanding, generation, and editing in the same visual space without a separate VAE pathway. System-level evaluations demonstrate practical text-to-image generation and instruction-based image editing, showing that a reparameterized pretrained ViT can serve as a unified visual interface for scalable multimodal modeling.

Jinbo Yan, Limeng Qiao, Jie Qin et al. · 0 citations
Aug 2026

GraESM-FuseDTA: adaptive gated multimodal fusion of graph neural networks and protein language models for robust drug-target affinity prediction.

Experiments show that GraESM-FuseDTA achieves competitive overall performance and consistent advantages in ranking-oriented and variance-explanation metrics across warm start, drug cold start, target cold start, and strict pair cold start settings.

Jun-Wen He · 0 citations