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Jun-Yan Ran

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Open access Sep 2026

Ent-abietane diterpenoid Enantiomers from Euphorbia helioscopia inhibits liver fibrosis via suppressing the TGF-β1/smad pathway

Mechanistic investigations revealed that the anti-fibrotic action of 1b in hepatic cells is probably mediated through the TGF-β/Smad signaling cascade, and position abietane-type diterpenoids as prospective molecular structures for the innovation of new therapeutics against liver fibrosis.

Li Jiang, Qian Wang, Jun-Yan Ran et al. · 0 citations

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