Open access
Sep 2026
Comparative transcriptome and proteome analysis of resistant and susceptible Talaromyces marneffei clinical isolates reveals a systemic multitiered defense network against azoles
ABSTRACT Talaromyces marneffei is a thermally dimorphic fungus causing life-threatening systemic mycosis in immunocompromised patients. The emergence of azole-resistant clinical isolates, especially those with reduced susceptibility to voriconazole (VOC) and fluconazole (FLC), presents a critical therapeutic challenge....
Yan-Qing Zheng, Gao-Yuan Peng, Xiao-Feng Pang et al.
· Antimicrobial Agents and Che... · 0 citations