Open access
Oct 2026
Dissolving hyaluronic acid microparticles improve skin barrier function, hydration, and elasticity in a randomized split-face clinical trial
The stratum corneum is a major barrier to topical delivery. We developed dissolving, star-shaped hyaluronic acid (HA) microparticles designed for fingertip rolling to create transient microchannels and support topical penetration. HA microparticles were fabricated using star-shaped micromolds and evaluated for geometry...
Hyunho Hwang, JinHee Koh, Huisuk Yang et al.
· Scientific Reports · 0 citations