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Author

Jung-Woo Han

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Open access Sep 2026

rAAV-mediated multi-miRNA delivery targeting MAPK pathway suppresses laser-induced choroidal neovascularization in mice

Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss, with neovascular AMD (nAMD) characterized by choroidal neovascularization (CNV) and subretinal fibrosis. Although anti-VEGF therapy is the current standard, frequent injections and limited efficacy necessitate alternative treatments....

Jung-Woo Han, Jin-Young Yang, Yeji Kim et al. · 0 citations
Open access Sep 2026

Retinal organoid-derived exosomes enhance retinal ganglion cell survival in chronic ocular hypertension

To date, the therapeutic potential of retinal organoid–derived exosomes (Exo-ROs) for retinal ganglion cell (RGC) preservation in chronic ocular hypertension (COH) has not been explored. We aimed to evaluate the neuroprotective effects and underlying molecular mechanisms of Exo-ROs in a rat COH model. Huma...

Si Hyung Lee, Jung-Woo Han, S. Yoon et al. · 0 citations

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