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Author

Junghee Lee

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Open access Jul 2026

Targeting the microglial phosphatidylethanolamine synthesis pathway promotes GABARAP-associated phagocytosis and Aβ clearance in Alzheimer’s disease

QA activates a microglia-specific signaling cascade that promotes PE biosynthesis and GAP, thereby enhancing Aβ clearance and mitigating AD pathology, and reveals a paradoxically beneficial role of QA in activating a microglia-specific signaling cascade that promotes PE biosynthesis and GAP.

Seung Jae Hyeon, Seungchan Kim, Jiyeon Chu et al. · 2 citations

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