Transcriptomics-Driven Identification and Engineering of a Novel Lactone Esterase (SrLE) for Efficient Sophorolipid Lactonization in the Yeast Starmerella riodocensis.
Lactonic sophorolipids (LSLs) are high-value glycolipid biosurfactants with superior bioactivities, yet their industrial application is hampered by the low lactonization efficiency of wild-type strains. In this study, we employed a transcriptomics-driven approach to decode the regulatory landscape of the underexplored...