Addressing the Abundance Paradox Through Topology‐Guided Graph Learning for Cross‐Cohort Classification of Type 2 Diabetes
ABSTRACT Gut microbiome‐based machine learning models for Type 2 Diabetes (T2D) classification often generalize poorly across cohorts due to population‐specific abundance variations—a practical challenge termed the abundance paradox. To capture conserved features beyond abundance, we developed DS‐GAT‐CP (Dual‐Stream Gr...