Preprint
Aug 2026
GenomeHarness: Harnessing Al Agents for Reliable Adaptation of Genome Language Models
GenomeHarness, an agentic harness for adapting genome language models through controlled search over fine-tuning recipes, improves mean test MCC in 47 settings, and shows gains on Genomic Benchmarks and on tasks where the root recipe is unstable or poorly matched.
Weicai Long, Yusen Hou, Houcheng Su et al.
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