Author

Junping Xie

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Review Aug 2026

Targeting the Ubiquitin-Proteasome System: An Emerging Paradigm for Overcoming Resistance to Targeted Therapy in Non-Small Cell Lung Cancer.

The molecular mechanisms by which the UPS contributes to targeted therapy resistance in NSCLC are summarized, recent progress in emerging UPS-targeting strategies are evaluated, and the major barriers impeding their clinical translation are critically discussed.

Ruizhi Chen, Hui Zhu, Kailang Zhou et al. · Experimental Cell Research · 0 citations