Open access
Jul 2026
PAX5 modulates vascularization and contributes to neuroendocrine lineage transition during carcinoma progression.
It is found that PAX5, a neural/lymphatic transcription factor, contributed to neuroendocrine (NE) lineage transition, and targeting PAX5 and its downstream signaling may modulate lineage transitions responsible for treatment failure in both SCNCs and adenocarcinomas.
Ailing Wu, Yujie Hao, Xuemiao Yan et al.
· Journal of Clinical Investig... · 0 citations