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Author

Juntaek Oh

2 papers indexed here

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Open access Sep 2026

Structural basis of transcription of the hachimoji eight-letter alphabet by E. coli RNA polymerase

Expanded genetic alphabets with synthetic nucleotides can greatly increase the chemical diversity of nucleic acids, enabling new molecular functions. Because cellular transcription is executed by multi-subunit RNA polymerases, the compatibility of unnatural base pairs with this machinery is essential for engineering ex...

Qing-Rong Li, Hyo-Joong Kim, Yan Liu et al. · 0 citations
Sep 2026

Structure-function analysis of access engineering in an FMNH2-dependent monooxygenase for enhanced polyethylene surface oxidation.

Enzymatic functionalization of polyethylene is fundamentally limited by a backbone consisting entirely of inert CH bonds, and a structural framework for enzyme-mediated PE oxidation remains limited. Here we identify PA2355 (FMO), a soluble FMNH2-dependent monooxygenase from Pseudomonas aeruginosa that hydroxylates untr...

Chanjoo Lee, Hong Rae Kim, Donggeon Choi et al. · 0 citations

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