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Junyoung Chang

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Open access Oct 2026

Spatiotemporally resolved single-nucleus transcriptomics reveals cellular and regional vulnerability in the midbrain in Parkinson’s disease

Parkinson’s disease (PD) is clinically and biologically heterogeneous, and ethnic differences may influence its pathogenesis. However, single-nucleus transcriptomic data from East Asian populations remain limited. Here, we present a spatially resolved single-nucleus transcriptomic atlas of the human substantia nigra (S...

Sooyeon Yoo, Kwanghoon Lee, Junseo Seo et al. · 0 citations
Open access Oct 2026

Prediction of Tumor Complete Response Using Genomic and Clinical Data in Solid Cancer Undergoing Definitive Radiation Therapy

In this retrospective, single-center observational study, targeted next-generation sequencing (NGS) was performed on pre-radiation therapy (RT) tumor specimens to identify genomic features associated with RT response and clinical outcomes. This study included 77 eligible patients with esophageal squamous cell carcinoma...

Junyoung Chang, Seung-Hyun Jung, Dong-Soo Lee · 0 citations

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