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Justin R. Kim

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Review Open access Sep 2026

Targeting Microglial Transcriptional Reprogramming as a Therapy Strategy for Alzheimer's Disease

ABSTRACT Recent human genetic studies revealed that Alzheimer's disease risk loci are enriched in genes expressed in myeloid cells, including microglia, the brain's resident immune cells. Notably, several risk‐associated genes, such as SPI1 and MEF2C, encode transcription factors (TFs) that control critical microglial...

Byungwook Kim, Selena S. Wang, Justin R. Kim et al. · 0 citations

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