Open access
Aug 2026
Myeloid cell expansion propels right ventricular dysfunction in HFpEF via sterile inflammation
Background Leukocyte’s role in frequently occurring right ventricular dysfunction (RVD) secondary to HFpEF remains poorly defined, partially due to the lack of suitable small animal models. Here, we followed a translational research approach by establishing a murine HFpEF model developing manifest RVD and analyzed huma...
L. Jaeschke, C. Koçana, A. M. Chitroceanu et al.
· Circulation · 0 citations