K. Abou-Daya

Regulatory CD4 T cells minimally migrate to inflamed allografts in the absence of effector T cell responses.

CD4+Foxp3+ regulatory T cells (Treg) are essential for maintaining immune tolerance in both lymphoid and non-lymphoid tissues, including transplanted organs. Understanding the mechanisms that regulate Treg suppressor function and tissue migration remains a major focus in transplantation immunobiology. Here, we show tha...