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Author

K. Al-Zahrani

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Open access Oct 2026

Functional identification of non-coding regulatory regions that drive breast and skin carcinogenesis.

Whole-genome sequencing has revealed hundreds of cancer driver mutations in protein-coding genes, while our knowledge of how non-coding mutations contribute to tumorigenesis remains limited. Here, we develop and perform large-scale functional screens to identify non-coding regulatory elements whose mutations drive canc...

Robin H. Oh, Kevin C. L. Cheng, Evgenija Serafimova et al. · 0 citations
Jul 2026

Parallel In Vivo Screening of Gene Knockout and Activation in the Mouse Mammary Gland.

A simple and versatile intraductal injection strategy that enables efficient and rapid functional genomic screening in the mouse mammary gland, by generating tens of thousands of discrete epithelial clones is described.

Ellen Langille, K. Al-Zahrani, Jocelyn Nurtanto et al. · 0 citations

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