Author

K. Albain

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Open access Oct 2026

Rilvegostomig Plus Trastuzumab-Deruxtecan for Early-Stage Breast Cancer

Importance The I-SPY2.2 trial tests personalized treatment strategies to improve outcomes while reducing exposure to standard chemotherapy in patients with high-risk early breast cancer (EBC). Objective To evaluate the efficacy and safety of trastuzumab-deruxtecan (T-DXd), an antibody drug conjugate targeting low ERBB2...

C. O'Sullivan, K. Kalinsky, C. Yau et al. · JAMA Oncology · 0 citations

Oct 2026

Unlocking 30-Year-Old Archival Formalin-Fixed Paraffin-Embedded Breast Cancer Specimens (SWOG S8897): An Analytical Feasibility Study.

PURPOSE Thin-cut formalin-fixed paraffin-embedded (FFPE) tumor sections on glass slides represent a large, underused biorepository for precision oncology, but their long-term room temperature storage raises concerns about nucleic acid integrity and analytical validity. We evaluated whether 20- to 30-year-old archival b...

Donald J. Johann, James B. Hicks, K. Albain et al. · JCO Precision Oncology · 0 citations