PURPOSE
Hyperthyroidism-associated liver injury represents an important extra-thyroidal complication of thyroid hormone excess, driven by increased metabolic demand and interconnected oxidative, inflammatory, and mitochondrial disturbances. However, the coordinated involvement of Nrf2/NF-κB signaling, apoptosis, and ir...
M. A. Ali, Khaled M. Alam-Eldein, Gannat Elsayed et al.· Tissue & Cell· 0 citations
Overall, this work establishes a docking-informed structure–interaction–property framework linking plant extract chemistry to electrospun CH/PVA textile performance for biomedical applications.
Hermela Ejegu, Mengdi Xu, Mesay Dubale Tigabu et al.· Journal of Industrial Textil...· 0 citations
RUT-SeNPs may represent a promising nanoformulation for reducing cisplatin-induced hepato-cardiac toxicity through coordinated modulation of oxidative stress, inflammation, endoplasmic reticulum stress, and apoptosis.
N. Mahran, Khaled M. Alam-Eldein, Mohamed A. Ali et al.· International Journal of Mol...· 1 citation
Pesticides play a crucial role in agriculture, public health management, and veterinary practice to control pests. However, the persistent use of pesticides poses a significant threat to aquatic ecosystems and non-target organisms, such as fish. The genotoxicity, oxidative stress, and erythrocytic toxicity were assesse...