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Author

K. Alsyaad

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Oct 2026

Quercetin-mediated selenium nanoparticles protect against hyperthyroidism-induced hepatic injury: Involvement of Nrf2/NF-κB signaling, mitochondrial apoptosis, and iron/heme imbalance.

PURPOSE Hyperthyroidism-associated liver injury represents an important extra-thyroidal complication of thyroid hormone excess, driven by increased metabolic demand and interconnected oxidative, inflammatory, and mitochondrial disturbances. However, the coordinated involvement of Nrf2/NF-κB signaling, apoptosis, and ir...

M. A. Ali, Khaled M. Alam-Eldein, Gannat Elsayed et al. · 0 citations
Open access Aug 2026

Electrospun chitosan/PVA nonwoven nanofiber mats functionalized with Lippia abyssinica extract: Molecular docking-assisted design and structure–property optimization

Overall, this work establishes a docking-informed structure–interaction–property framework linking plant extract chemistry to electrospun CH/PVA textile performance for biomedical applications.

Hermela Ejegu, Mengdi Xu, Mesay Dubale Tigabu et al. · 0 citations
Open access Aug 2026

Rutin-Functionalized Selenium Nanoparticles Attenuate Cisplatin-Induced Cardiohepatic Injury in Rats: Modulation of ER Stress-Related Gene Expression and Mitochondrial Apoptotic Markers

RUT-SeNPs may represent a promising nanoformulation for reducing cisplatin-induced hepato-cardiac toxicity through coordinated modulation of oxidative stress, inflammation, endoplasmic reticulum stress, and apoptosis.

N. Mahran, Khaled M. Alam-Eldein, Mohamed A. Ali et al. · 1 citation
Open access Jul 2026

Integrated assessment of thiram toxicity in pangasius fish: Erythrocytic abnormalities, gill and intestinal defense mechanisms, and genotoxicity

Pesticides play a crucial role in agriculture, public health management, and veterinary practice to control pests. However, the persistent use of pesticides poses a significant threat to aquatic ecosystems and non-target organisms, such as fish. The genotoxicity, oxidative stress, and erythrocytic toxicity were assesse...

Nimra Sageer, Areeb Nawaz, Riaz Hussain et al. · 0 citations

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