Author

K. Alzahrani

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Open access Sep 2026

Antihemolytic Activity, Bioactive Metabolites, and TEM‐1 β‐Lactamase Inhibition Potential of Fumaria parviflora Extract Against Blood‐Borne Extensively Drug‐Resistant Salmonella typhi : A First Study

In the present study, the aqueous leaf extract of Fumaria parviflora ( F. parviflora ) was evaluated against blaTEM‐1‐positive extensively drug‐resistant (XDR) Salmonella typhi ( S. typhi ) to identify bioactive compounds and investigate putative inhibitors of TEM‐1 β‐lactamase in XDR S. typhi . Blood sam...

Khalaf F. Alsharif, K. Alzahrani, F. M. Alzahrani et al. · ChemistrySelect · 0 citations

Aug 2026

Glucose-oxidase-integrated zinc-based metal-organic framework (GOx@ZIF-8) nanoparticles as a dual pH/glucose-responsive insulin delivery system for type 2 diabetes management: Synthesis, characterization, and in vitro/in vivo evaluation.

Type 2 diabetes mellitus (T2DM) affects over 537 million adults worldwide; conventional insulin therapy suffers from poor oral bioavailability, enzymatic degradation, and hypoglycemia risk. We developed a dual pH- and glucose-responsive PEG-GOx@ZIF-8-Ins nanoplatform for oral insulin delivery via biomimetic co-precipit...

Debakar Roy, S. Mohammad, A. Vasudevan et al. · Nanomedicine: Nanotechnology... · 0 citations

Sep 2026

Chronic labetalol exposure induced dose-dependent testicular toxicity via disruptingt HPG-axis, spermatogenesis and steroidogenic pathways: A biochemical, molecular and histopathological evidence.

Labetalol (LBL) is a combined-alpha and non-selective β-adrenergic receptor antagonist commonly prescribed for high blood pressure patients. However, LBL intoxication showed severe toxicity including testicular impairments. This experimental study aimed to elucidate the dose-responsive reproductive perturbations of LBL...

Salim Jamil, F. M. Alzahrani, Khalaf F. Alsharif et al. · Tissue & Cell · 0 citations

Aug 2026

Toward a Vaccine Against Multidrug-Resistant Elizabethkingia anophelis: Comprehensive Immunoinformatics-Based Design of a Multi-Epitope Vaccine and mRNA Construct.

This computationally designed hybrid multi-epitope vaccine (MEV) was designed using an extensive immunoinformatics approach targeting four key outer membrane and secretion-associated proteins and offers a promising preventive strategy against E. anophelis infections.

Muhammad Hanzala, Rana Zohaib Abbas, Mahnoor Habib et al. · Probiotics and Antimicrobial... · 0 citations

Review Open access Jul 2026

Host and Pathogen Genetic Determinants of Brucellosis in Veterinary–One Health Interface: A Review

Practical advances most relevant to veterinary practice are highlighted: genetic markers that may contribute to breeding programs after independent validation to produce naturally resistant cattle, goats, sheep, and buffalo, and gene-expression signatures that may sharpen diagnosis and disease staging.

Abdul Qadeer, M. Tharwat, Ibrahim F. Halawani et al. · Veterinary Sciences · 0 citations