Lung and breast cancers are among the major causes of cancer-related morbidity and mortality worldwide. Both these cancers share several dysregulated molecular processes, including common oncogenic signaling pathways and molecular targets. Therefore, the current study focuses on the dual anticancer potential of Annona...
S. Patil, Abhijit Das, K. Asgaonkar et al.· Computers in Biology and Med...· 0 citations
Breast cancer remains a leading cause of death among women, with one
life lost approximately every 13 minutes. Postmenopausal women are particularly susceptible to
Estrogen Receptor-positive (ER+) breast cancer. Aromatase inhibitors, including letrozole, exemestane, and anastrozole, suppress estrogen synthesis in p...
T. Chitre, K. Asgaonkar, Sonali S. Shelake et al.· Clinical Cancer Drugs· 0 citations
INTRODUCTION
Sida cordifolia (SC) is traditionally used for treat inflammatory disorders; however, its molecular composition and the mechanistic basis of action remain poorly characterized. This study aimed to identify its bioactive constituents and elucidate their multi-target anti-inflammatory potential using an inte...
K. Asgaonkar, A. Avalaskar, K. Rajagopal et al.· Current Computer - Aided Dru...· 0 citations
The results indicate that electronic and steric factors around the 4-aminoquinoline nucleus strongly influence anticancer activity, and the optimised pharmacophore provides a framework for designing new, more potent anticancer agents.
S. Patil, K. Asgaonkar, Darshani Gholap et al.· Current Enzyme Inhibition· 0 citations
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