The murine correlate of the Epstein-Barr and Kaposi's sarcoma-associated γ-herpesviruses, MHV-68, represents a valuable model to assess antiviral drug sensitivity and combinatorial drug synergies.
Human herpesviruses represent major human pathogens. Members of the γ-Herpesvirinae subfamily are of particular interest because they cause chronic diseases, such as cancers, by altering cellular processes and driving resting cells into a continuously proliferating phase. Also, autoimmune diseases such as multiple scle...