Open access
Aug 2026
Synthesis and Activity-Based Protein Profiling Identifies Aldo-Keto Reductase 1C3 as Target Protein of Myxoglucamides.
The identification of aldo-keto reductase 1C3 (AKR1C3) as the primary target of myxoglucamides in human cells implies that the search for targets of natural products is rewarding even in the absence of an initial phenotypic activity.
Thomas Siemon, Vivek K. Mishra, Mingming Zhao et al.
· Angewandte Chemie · 0 citations