Preclinical and clinical evaluation of the kappa opioid receptor as a therapeutic target in multiple sclerosis
Multiple sclerosis (MS) is a chronic, inflammatory, and neurodegenerative disease for which there is no cure. Aotearoa, New Zealand is a high-risk country for MS with an overall prevalence of 73.1 per 100,000 population, compared to the global prevalence of 35.9. The progression of MS treatments is impeded by the dual-...