Abstract Background Treatment resistance in anxiety disorders (TR-AD) constitutes a major clinical challenge, affecting a substantial proportion of patients despite the availability of evidence-based pharmacological and psychotherapeutic interventions. Aims & Objectives This talk will present a consensus definition of...
K. Domschke· International Journal of Neu...· 0 citations
Psychiatric syndromes can be caused by underlying autoimmune encephalitis (AE). This represents a diagnostic challenge at the interface of psychiatry and neurology. While AE mostly manifests with a combined, complex neuropsychiatric syndrome, some patients with AE may (initially) present with predominant or isolated ps...
D. Endres, K. von Zedtwitz, Ludger Tebartz van Elst et al.· Molecular Psychiatry· 0 citations
Effective evidence-based treatments for OCD are already available, and promising new approaches are being studied, including Bergen four-day treatment, Internet-based and virtual therapies, and glutamatergic agents.
Ulrich Voderholzer, Lena Jelinek, Rebecca Schennach et al.· Deutsches Ärzteblatt Interna...· 0 citations
The pathophysiology of depression involves multiple biological processes, including circuit dysfunction and impaired neuroplasticity, yet an integrative view linking these processes remains elusive. Here, we identify a convergent circuit for antidepressant response and plasticity modulation. We demonstrate that chemoge...
M. Veleanu, Louise Schuberth, Antje Kilias et al.· Nature Communications· 0 citations
Social anxiety disorder (SAD) is a common anxiety disorder (ANX) with moderate heritability that often co-occurs with other mental disorders. Until now, sample sizes in genetic analyses of SAD have been limited, so that the genetic basis of SAD and its subphenotypes is still largely unknown. In a large cohort comprisin...
L. Sindermann, Angelina Röhrig, F. David et al.· Translational Psychiatry· 0 citations
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