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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

K. El Koulali

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Open access Jul 2026

Multi-omics characterization of IDH-mutant astrocytoma-derived cell lines reveals NOTCH-regulated plastic quiescent astrocyte-like state and insights into progression.

Four astrocytoma cell lines derived from IDH-mutant astrocytomas are established and extensively characterized and evidence that NOTCH signaling contributes to the regulation of cell state balance, promoting transitions toward an astrocyte-like transcriptional program while DLL3, an anti-Notch protein, expressed by oli...

L. Garcia, C. Granotier-Beckers, D. Pineau et al. · 0 citations

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