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Author

K. Higasa

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2 papers indexed here

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Sep 2026

Differential regulation of CYP46A1 in ischemic core and peri-infarct regions of male mouse brain after permanent middle cerebral artery occlusion.

Cholesterol 24-hydroxylase (CYP46A1) regulates brain cholesterol homeostasis and synaptic plasticity, playing a crucial role in ischemic stroke. Although previous studies have reported post-ischemic CYP46A1 upregulation, its spatiotemporal dynamics remain poorly defined. To elucidate these dynamics, we investigated the...

Hikaru Iwashita, Souichi Oe, Y. Hirahara et al. · 0 citations
Open access Aug 2026

Exercise and Cardiorespiratory fitness Improvement through supervised TraINinG in patients undergoing surgery for Upper GastroIntestinal cancer (EXCITING-UGI): study protocol for a randomized controlled trial

This study aims to compare the effects of HIIT and LICT on the postoperative recovery of patients with upper gastrointestinal cancer, and may provide clinically relevant evidence for optimizing exercise intensity in the early postoperative phase.

Takuya Fukushima, Makoto Yamasaki, Nobuyuki Yamamoto et al. · 0 citations

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