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K. Hoang

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Sep 2026

Surgery and tile-based radiation therapy versus surgery and stereotactic radiation for newly diagnosed brain metastases (ROADS): a randomized, open-label, phase 3 trial.

PURPOSE Post-operative stereotactic radiation (SRT) is the standard-of-care for resected brain metastases. Implantation of cesium-131 collagen tiles (tile-based radiation therapy, TBRT) initiates focal radiation immediately after resection, potentially offering therapeutic and logistical advantages. ROADS: a randomized...

J. Weinberg, B. Imber, V. Dinapoli et al. · 0 citations
Open access Aug 2026

PACM-03 TUMOR–BRAIN CROSSTALK DRIVES NEURAL MICROENVIRONMENT REMODELING AND PROMOTE DEMYELINATION IN BRAIN METASTASES

It is demonstrated that BM actively disrupt myelin homeostasis and neural signaling within surrounding brain tissue, and this ex-vivo platform provides a robust experimental system to study tumor–brain interactions and to evaluate therapeutic strategies aimed at limiting tumor-induced neurological damage.

Y. Zohdy, Arman Jahangiri, Amelia Tong et al. · 0 citations
Review Open access Aug 2026

Integrating single-cell transcriptomics with deep learning for glioblastoma treatment

How scRNA-seq can be used to identify important areas of glioblastoma treatment resistance, evaluate current glioblastoma scRNA-seq-based deep learning models, and outline relevant training datasets to overcome patient scRNA-seq data availability limitations are explained.

Marybeth G. Yonk, Mainak Mustafi, Megan A Lim et al. · 0 citations

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