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Author

K. Hornung

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Open access Sep 2026

Intracellular Ca2+ balances the anti-inflammatory potential of IL-33-activated mast cells (MCs).

IL-33 is an alarmine released upon tissue injury. Mast cells (MCs) highly express the IL-33 receptor T1/ST2 (IL-33R) and are thus highly susceptible to released IL-33. Activation of the IL-33R on MCs induces the MyD88-dependent activation of the TAK1-IKK2-p65/RelA signaling pathway, ERK1/2 and p38 which together mediat...

S. Wagner, Claudia Küchler, K. Hornung et al. · 0 citations

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