Open access
Jul 2026
Endogenous Retrovirus Neoantigen Enables Personalized Cancer Vaccine in glioblastoma, IDH-wildtype 2259068
ERVs are consistently expressed and immunogenic in GBM, representing a scalable, tumor-specific antigen source that may overcome limitations of low mutational burden and provide a proof-of-concept for personalized vaccines targeting ERV-derived neoantigens.
Kenan Zhang, Megan C. Benz, K. Hotchkiss et al.
· Journal of Immunology · 0 citations