Open access
Aug 2026
Regiospecific α-arylation of diverse carbonyl compounds using an organobismuth transporter
The α-arylation of carbonyl compounds is a cornerstone transformation in the synthesis of pharmaceuticals and natural products. Despite decades of effort using transition metal, main-group, and photoredox strategies, a general and practical α-arylation method with broad substrate scope has remained elusive. Here we sho...
Li Li, Filippo Carpaneto, Pan-Pan Chen et al.
· Nature Chemistry · 0 citations