Author

K. Iskandar

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Open access Oct 2026

Serum HMGB1 and TLR4 Levels in Pediatric Drug-Resistant Epilepsy: Associations and Preliminary Discriminatory Performance

Serum HMGB1 and TLR4 levels were associated with pediatric DRE and higher seizure frequency, supporting their potential role as exploratory inflammatory biomarkers, however, their modest specificity and the single-center cross-sectional design preclude their use as standalone diagnostic tests.

A. P. Nugrahanto, A. Triono, D. Nurputra et al. · Annals of Child Neurology · 0 citations

Review Aug 2026

Whole-exome sequencing in pediatric drug-resistant epilepsy: diagnostic yield and clinical impact in a resource-limited setting

WES can yield a definitive genetic diagnosis in a subset of patients, enabling individualized management, facilitating genetic counseling, and reducing the need for further diagnostic investigations.

E. S. Herini, A. Triono, K. Iskandar et al. · Neurogenetics · 0 citations