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Author

K. Jähn-Rickert

2 papers indexed here

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Open access Sep 2026

Multiscale assessment of glucocorticoid-induced alterations across bone marrow and mineralized bone in human iliac crest biopsies.

BACKGROUND Glucocorticoid-induced osteoporosis (GIOP) is associated with a fracture risk that exceeds what would be expected based on bone mineral density (BMD) alone, suggesting impaired bone quality. In contemporary clinical practice, patients receiving glucocorticoids are typically treated concomitantly with anti-os...

P. Sihota, Xenia Junimann, Johannes Krug et al. · 0 citations
Open access Aug 2026

Oxygen-dependent osteocyte transcriptomic adaptations occur without modulation of endothelial gene expression via osteocyte paracrine signaling

Abstract Bone regeneration remains a significant clinical challenge, requiring a deeper understanding of the cellular and molecular mechanisms underlying bone repair. Osteocytes, which represent 90%-95% of bone cells, form a connective dendritic network and play a key role in skeletal homeostasis. Embedded within the m...

Léa Gellée, F. Martins, Alexandre Brochard et al. · 1 citation

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