K. Jamialahmadi

Dendrimers in precision oncology: advances in therapy, diagnostics, and translational prospects.

Dendrimers are highly branched nanoscale macromolecules with precisely tunable architectures that have emerged as transformative tools in cancer research. Their unique properties, such as high drug-loading capacity, multivalency, and surface tailoring ability, enable innovative applications in drug delivery, gene thera...

The TLR4/MyD88 axis in cancer: divergent and convergent roles of NF-κB and NLRP3 inflammasome activation and therapeutic opportunities.

The TLR4/MyD88 signaling axis serves as a central hub linking microbial- and damage-associated molecular patterns to oncogenic inflammation. Upon ligand engagement, MyD88 orchestrates two major downstream branches, including the canonical NF-κB pathway, which drives transcriptional programs for cell survival, prolifera...

Smart drug delivery systems for immunotherapeutic agents: focus on biological/biogenic platform-based intelligent delivery in cancer immunotherapy.