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Open access Oct 2026

TIA1 is required for microglial activation in tauopathy.

The RNA-binding protein T cell intracellular antigen-1 (TIA1) regulates cellular stress responses and tau pathology, key contributors to the pathophysiology of tauopathies, including Alzheimer's disease (AD). TIA1 acts in peripheral monocytes to inhibit inflammation, but its function in central microglia, critical to n...

C. J. Webber, S. V. D. van der Spek, A. L. Cruz et al. · 0 citations
Open access Aug 2026

Sex-specific genotype-phenotype landscape and prevalence of CASK-related disorder

How variant type and X-linked inheritance jointly shape disease expression is revealed and provide a foundation for improving diagnosis, genetic counseling, natural history studies, therapeutic development, and health policy planning for CASK-related disorder, with broader implications for other X-linked neurodevelopme...

K. Jiang, Ş. Aras, M. Xue · 0 citations

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