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Open access Sep 2026

Dermal bone remodelling by invasive osteoblasts evolved in stem gnathostomes

The evolutionary origin of the human face can be traced to the earliest vertebrates with a dermal skeleton in which canonical skeletal tissues and cell types arose. To elucidate its developmental evolution we performed genetic mosaic labelling, 3D single cell analysis and fluorescent matrix birthdating in vivo. We disc...

K. Jordan, Jason P. Downs, Xin-Tao Zhang et al. · 0 citations

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