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Open access Oct 2026

Melatonin protects keratinocytes from diesel-derived PM2.5-induced damage by suppressing JNK/p38 MAPK signaling and caspase activation.

Melatonin is a naturally produced hormone in the human body that primarily regulates the sleep-wake cycle. This study examined the role of melatonin in protecting human keratinocytes from diesel-derived particulate matter 2.5 (DPM2.5)-induced oxidative injury. HaCaT keratinocytes and male HR-1 hairless mice were expose...

Mei-Jing Piao, K. Kang, H. Senavirathna et al. · 0 citations
Jul 2026

Luteolin reverses chemoresistance in colorectal cancer cells via TET1/TDG-dependent epigenetic repression of β-catenin.

It is demonstrated that luteolin reverses chemoresistance by suppressing the TET1/TDG-β-catenin axis through epigenetic regulation and modulation of intracellular redox homeostasis, supporting its potential as an adjuvant for CRC chemotherapy.

K. Kang, Mei-Jing Piao, H. Senavirathna et al. · 0 citations

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