Melatonin protects keratinocytes from diesel-derived PM2.5-induced damage by suppressing JNK/p38 MAPK signaling and caspase activation.
Melatonin is a naturally produced hormone in the human body that primarily regulates the sleep-wake cycle. This study examined the role of melatonin in protecting human keratinocytes from diesel-derived particulate matter 2.5 (DPM2.5)-induced oxidative injury. HaCaT keratinocytes and male HR-1 hairless mice were expose...