Author

K. Karczewski

2 papers indexed here

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Open access Aug 2026

A unified framework for local-ancestry-aware genetic association analysis across biobanks

Biobanks increasingly include individuals with admixed genomes, yet conventional genome-wide association study frameworks either exclude participants who cannot be confidently assigned to a discrete ancestry group or ignore ancestry-specific effects. We present FELIX, a scalable framework for local-ancestry-aware genet...

L. Hu, T. Tan, K. Yuan et al. · medRxiv · 0 citations

Open access Aug 2026

A 515,579-Genome Reference Panel Improves Rare-Variant Imputation Across Multiple Underrepresented Populations

A cloud-based imputation service built on a multi-ancestry reference panel derived from 515,579 jointly phased genomes from the All of Us and AnVIL datasets, establishing a new foundation for genome-wide association studies (GWAS) and fine-mapping, especially in previously underrepresented populations.

Franjo Ivankovic, A. Ko, M. Aster et al. · medRxiv · 0 citations