K. Koenen

Associations Between Mental Health Diagnoses and Recurrent Acute Care Use Among Individuals with Systemic Lupus Erythematosus in the All of Us.

OBJECTIVE We investigated prospective associations between mental health conditions (depression, anxiety, and post-traumatic stress disorder, PTSD) and recurrent acute care use among patients with systemic lupus erythematosus (SLE). METHODS Within All of Us Research Program (version 8), a US-wide cohort of adults enr...

Stress sensitization: does childhood adversity modify trauma effects on memory?

Background Trauma across the lifecourse is implicated in adverse health outcomes, yet whether earlier adversity shapes vulnerability to effects of later trauma on cognitive decline, an important contributor to Alzheimer's disease, remains unclear. Objective We examined the impact of adult incident traumatic experiences...

Psychological Resilience to Trauma and Risk of Metabolic Syndrome in Women.

Future research on trauma and MetS should consider varied trauma responses and assess if interventions that not only reduce psychological distress but also promote PWB could mitigate MetS risk.

Ancestry-Calibrated Polygenic Risk Scores Predict PTSD Trajectories in Recent Trauma Survivors and Interact with Neighborhood Resources

Objective: Polygenic risk scores (PRS) for posttraumatic stress disorder (PTSD) often account for a low amount of variance. Ancestry-related differences in PRS scale and variance limit cross-group comparisons. This methodological challenge further complicates gene-by-environment (GxE) analyses, given that socioenvironm...

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